I'm where you are. I've been home almost 14 years now, but because we homeschool, my kids are still home and will continue to be as long as they wish (which could be the next 9 years).
I've been restless lately. Not that my current job isn't demanding or that I'm bored ~ oy, far from it...I just want to do something
else for a bit. Plus I recognize that if I wait until my younger daughter is done with her education, I could end up being 20 years out of the workforce! Perhaps this is unavoidable in some cases, but it bugs me.
I applied for a couple of part time, entry level jobs at local libraries but didn't get them. I couldn't tell you why, but obviously I didn't look great on paper.
I thought I did a great job filling out the application, so I believe I represented myself well. Maybe it was the long layoff from work. Maybe it was the homeschooling. Or perhaps the lack of education. I may have a lot of strikes against me.
Anyway, after talking to some people who were kind enough to offer advice, I've come up with the plan to volunteer for a bit. That way, there's a good chance I'll get hired (after all, I'm free labor!), and I'll gain some experience. Ideally, in time I'll have something "substantial" in a potential employer's eyes to put on a resume.
Taking classes is a great idea too. I'm already knee deep in schoolwork, so I'm putting that on hold for now, but if your schedule is open enough, that would be awesome for you!
You have my empathy and support.

((hug)) If we're lucky, some of our fellow Catheites will offer up suggestions.